with MD Pens’s Radiant Retinol 1% Balancing Complex. My skin took to it easily. I noticed an increased softness in my skin after one use. I applied it after cleansing and using MD Pen’s serum. It is thick enough to use as a night cream, but not heavy or greasy. It did not feel like it would be all rubbed off on my pillow. It was mostly absorbed and left a nice moisture barrier on my skin. This cream is not just a retinol but a great night cream that has antioxidants, niacinamide, probiotics, and prebiotics. I often use retinol, so I had no issues using this nightly for a week straight. Those with sensitive skin will want to go slowly and space out use.